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TeachMeFinance.com - explain blood-brain barrier disruption blood-brain barrier disruption BBBD. The use of drugs to create openings between cells in the blood-brain barrier. The blood-brain barrier is a protective network of blood vessels and tissue that protects the brain from harmful substances, but can also prevent anticancer drugs from reaching the brain. Once the barrier is opened, anticancer drugs may be infused into an artery that goes to the brain, in order to treat brain tumors. About the author Mark McCracken Author: Mark McCracken is a corporate trainer and author living in Higashi Osaka, Japan. He is the author of thousands of online articles as well as the Business English textbook, "25 Business Skills in English". Copyright © 2005 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Source of definition: The National Cancer Institute. Please read the disclaimer for details.