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TeachMeFinance.com - explain Mammotome Mammotome -- A device that uses a computer-guided probe to perform breast biopsies. A Mammotome biopsy can be done on an outpatient basis with a local anesthetic, removes only a small amount of healthy tissue, and doesn�ft require sutures (stitches) because the incision is very small. Copyright © 2005 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Source of definition: The National Cancer Institute. Please read the disclaimer for details.