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TeachMeFinance.com - explain Interstate Commerce Clause Interstate Commerce Clause A clause of the U.S. Constitution which reserves to the federal government the right to regulate the conduct of business across state lines. Under this clause, for example, the U.S. Supreme Court has ruled that states may not inequitably restrict the disposal of out-of-state wastes in their jurisdictions. About the author Mark McCracken Author: Mark McCracken is a corporate trainer and author living in Higashi Osaka, Japan. He is the author of thousands of online articles as well as the Business English textbook, "25 Business Skills in English". Copyright © 2005 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Please read the disclaimer for details.