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TeachMeFinance.com - explain SecDef SecDef 'SecDef' is an abbreviation standing for 'Secretary of Defense'. Previous 5 Terms: SYS SYSCOM SYSCON SZ Sealift Readiness Program Next 5 Terms: Secretary of a Military Department Selected Reserve Service component command Service force module Service-common Copyright © 2005-2011 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Please read the disclaimer for details.